Arjen M Dondorp Selected Research

Quinine (Quinson)

1/2017	Defining Surrogate Endpoints for Clinical Trials in Severe Falciparum Malaria.
1/2017	Measuring the Plasmodium falciparum HRP2 protein in blood from artesunate-treated malaria patients predicts post-artesunate delayed hemolysis.
2/2014	Malaria.
1/2014	Randomized controlled trial of levamisole hydrochloride as adjunctive therapy in severe falciparum malaria with high parasitemia.
2/2013	Population pharmacokinetic and pharmacodynamic properties of intramuscular quinine in Tanzanian children with severe Falciparum malaria.
10/2012	Diagnosis, clinical presentation, and in-hospital mortality of severe malaria in HIV-coinfected children and adults in Mozambique.
4/2012	Predicting the clinical outcome of severe falciparum malaria in african children: findings from a large randomized trial.
1/2012	Diagnosing severe falciparum malaria in parasitaemic African children: a prospective evaluation of plasma PfHRP2 measurement.
7/2011	Cost-effectiveness of parenteral artesunate for treating children with severe malaria in sub-Saharan Africa.
11/2010	Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial.

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Arjen M Dondorp Research Topics

Disease

149	Malaria 10/2022 - 02/2004
104	Falciparum Malaria (Plasmodium falciparum Malaria) 10/2022 - 08/2004
39	Infections 10/2022 - 08/2006
13	Hemolysis 10/2022 - 01/2014
12	Sepsis (Septicemia) 01/2021 - 06/2007
11	Vivax Malaria 09/2021 - 04/2010
10	Coma (Comas) 01/2019 - 01/2009
9	Parasitemia 01/2019 - 08/2007
8	Acute Kidney Injury (Acute Renal Failure) 10/2022 - 08/2011
7	COVID-19 04/2022 - 01/2020
7	Cerebral Malaria 10/2021 - 07/2009
7	Acidosis 01/2019 - 08/2004
6	Hypoxia (Hypoxemia) 10/2021 - 05/2018
6	Glucosephosphate Dehydrogenase Deficiency 01/2021 - 01/2014
6	Body Weight (Weight, Body) 01/2018 - 07/2009
5	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2022 - 01/2018
5	Reinfection 01/2020 - 09/2008
4	Pneumonia (Pneumonitis) 03/2021 - 01/2013
4	Anemia 01/2019 - 10/2012
4	Melioidosis 01/2013 - 06/2007
3	Vomiting 01/2022 - 01/2020
3	Critical Illness (Critically Ill) 01/2021 - 10/2017
3	Coinfection 12/2020 - 03/2016
3	Fever (Fevers) 01/2019 - 11/2015
3	Hypovolemia 04/2013 - 01/2009
2	Septic Shock (Toxic Shock Syndrome) 01/2021 - 11/2017
2	Lactic Acidosis 03/2019 - 04/2013
2	Scrub Typhus (Typhus, Scrub) 09/2018 - 04/2005
2	Brain Edema (Cerebral Edema) 01/2018 - 08/2011
2	Pulmonary Tuberculosis 10/2017 - 12/2015
2	Tuberculosis (Tuberculoses) 10/2017 - 09/2015
2	Typhoid Fever (Typhoid) 07/2017 - 01/2017
2	Inflammation (Inflammations) 07/2017 - 01/2016
2	Hemorrhage 01/2017 - 05/2016
2	Bacterial Infections (Bacterial Infection) 11/2015 - 01/2011

Drug/Important Bio-Agent (IBA)

72	artemisinin (artemisinine)IBA 04/2022 - 11/2008
40	Antimalarials (Antimalarial Agents)IBA 01/2022 - 11/2008
31	ArtesunateIBA 01/2022 - 07/2007
26	Pharmaceutical PreparationsIBA 01/2022 - 09/2007
17	Primaquine FDA Link 09/2021 - 01/2012
15	piperaquineIBA 10/2021 - 04/2010
13	artenimol (dihydroartemisinin)IBA 01/2020 - 04/2010
13	Lactic Acid (Lactate)FDA LinkGeneric 03/2019 - 08/2004
13	Quinine (Quinson)FDA Link 01/2017 - 07/2007
9	Proteins (Proteins, Gene)FDA Link 01/2022 - 04/2005
9	Histidine (L-Histidine)FDA Link 01/2022 - 08/2012
8	Biomarkers (Surrogate Marker)IBA 01/2021 - 03/2014
7	AntigensIBA 01/2022 - 08/2005
7	Mefloquine (Lariam)FDA LinkGeneric 10/2021 - 04/2009
7	AcidsIBA 01/2019 - 08/2004
6	Hemoglobins (Hemoglobin)IBA 10/2022 - 01/2017
6	AntibodiesIBA 01/2022 - 08/2006
6	ArtemisininsIBA 02/2021 - 08/2011
5	CreatinineIBA 10/2022 - 08/2011
5	Acetaminophen (Paracetamol)FDA LinkGeneric 10/2022 - 04/2016
5	Lumefantrine Drug Combination Artemether (Coartem)FDA Link 01/2022 - 09/2008
5	Oxygen (Dioxygen)IBA 01/2022 - 08/2012
5	Retinaldehyde (Retinal)IBA 05/2016 - 07/2009
4	DNA (Deoxyribonucleic Acid)IBA 12/2021 - 04/2015
4	Glucosephosphate Dehydrogenase (Glucose 6 Phosphate Dehydrogenase)IBA 01/2021 - 01/2014
4	8-aminoquinolineIBA 01/2021 - 03/2016
4	pyrimethamine drug combination fanasil (Fansidar)FDA Link 07/2020 - 03/2013
4	Immunoglobulin M (IgM)IBA 01/2019 - 08/2006
4	CytokinesIBA 07/2017 - 06/2007
3	Amodiaquine (Camoquin)FDA Link 01/2022 - 12/2013
3	Folic Acid AntagonistsIBA 07/2020 - 09/2016
3	Chloroquine (Aralen)FDA LinkGeneric 10/2019 - 04/2010
3	Urea (Carbamide)FDA LinkGeneric 01/2019 - 08/2011
3	Heme (Haem)IBA 04/2018 - 10/2007
3	Granzymes (Granzyme)IBA 07/2017 - 04/2005
3	Acetylcysteine (Siran)FDA LinkGeneric 02/2009 - 02/2004
3	Messenger RNA (mRNA)IBA 02/2009 - 06/2007
2	VaccinesIBA 01/2022 - 01/2020
2	Lipocalin-2IBA 10/2021 - 03/2014
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 11/2015
2	N 30IBA 01/2021 - 08/2011
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2020 - 06/2018
2	Amino Acids FDA Link 01/2019 - 11/2018
2	NitrogenIBA 01/2019 - 08/2011
2	Immunoglobulin G (IgG)IBA 01/2019 - 01/2019
2	Mannitol (Osmitrol)FDA LinkGeneric 01/2018 - 08/2011
2	Crystalloid SolutionsIBA 11/2017 - 04/2013
2	F2-Isoprostanes (F2 Isoprostanes)IBA 01/2017 - 02/2009
2	Heparin (Liquaemin)FDA LinkGeneric 01/2017 - 01/2017
2	sevuparinIBA 01/2017 - 01/2017
2	proguanil drug combination atovaquone (malarone)FDA Link 01/2017 - 09/2014
2	C-Reactive ProteinIBA 01/2016 - 11/2015
2	Levamisole (Decaris)FDA Link 01/2014 - 08/2007

Therapy/Procedure

41	Therapeutics 01/2022 - 12/2007
22	Mass Drug Administration 11/2021 - 01/2012
9	Critical Care (Surgical Intensive Care) 01/2021 - 01/2011
5	Positive-Pressure Respiration (Positive End-Expiratory Pressure) 01/2022 - 01/2018
5	Blood Transfusion (Blood Transfusions) 01/2022 - 11/2014
5	Resuscitation 01/2020 - 08/2012
3	Length of Stay 01/2022 - 01/2011
3	Aftercare (After-Treatment) 01/2019 - 05/2010
3	Insecticide-Treated Bednets 11/2018 - 09/2014
2	Mechanical Ventilators (Ventilator) 11/2021 - 01/2020
2	Artificial Respiration (Mechanical Ventilation) 01/2018 - 11/2017
2	Renal Replacement Therapy (Therapies, Renal Replacement) 01/2017 - 08/2011